Proteinuria in Chronic kidney disease
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Dr. Smarak Ranjan Panda
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Proteinuria, the presence of excess protein in the urine, is a key indicator of kidney damage in chronic kidney disease (CKD). It occurs due to glomerular injury, which increases the permeability of the filtration barrier and allows proteins like albumin to enter the urine.1 Proteinuria is both a marker of kidney dysfunction and a risk factor for disease progression. The level of proteinuria is directly related to the severity of kidney damage and the risk of progressing to end stage renal disease. 2 Management includes controlling blood pressure, especially with angiotensin converting enzyme inhibitors or angiotensin receptor blockers, along with tight blood sugar control in diabetic patients, lifestyle changes, and regular monitoring of protein levels to evaluate CKD progression and treatment response.