Nephrotic syndrome is characterized by hypoalbuminemia, severe proteinuria, and peripheral edema, usually in conjunction with hyperlipidemia.[1] The condition may be idiopathic or can originate due to diverse secondary causes. Nephrotic syndrome may also give rise to complications, such as infections, hypocalcemia, bone abnormalities, hyperlipidemia, atherosclerosis, hypercoagulability, and hypovolemia. For diagnosis, blood tests, including serum albumin, total cholesterol and triglycerides, and creatinine assessment, are warranted. Testing for secondary causes is also recommended. Imaging tests include ultrasonography, renal biopsy tests, and autoantibodies against PLAR.[2] Management involves edema control via fluid and dietary restriction coupled with loop diuretics. Hospital admission may be needed for unresponsive patients.
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